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Targets Recommended: Glucagon Receptor

26

抑制剂 & 化合物

39

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TQ0239 PF-06291874

Glucagon receptor antagonists-4

Glucagon Receptor GPCR/G Protein
PF-06291874 (Glucagon receptor antagonists-4) 是口服有活性的胰高血糖素受体非肽类拮抗剂。它正用于研究 2 型糖尿病。
T19814 CP-380736

PF 00520893,CP380736,PF00520893,6,7-二甲氧乙氧基喹唑啉-4-酮,CP 380736,PF-00520893

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
CP-380736 (PF-00520893) 是一种表皮生长因子受体 (EGFR) 抑制剂。 EGFR 是一种酪氨酸激酶,可激活 MAPK、JNK 和 Akt 通路,是多种癌症的重要介质。
T5508 PF-AKT400

(S)-N-[[3-氨基-1-(5-乙基-7H-吡咯并[2,3-D]嘧啶-4-基)吡咯烷-3-基]甲基]-2,4-二氟苯甲酰胺,AKT protein kinase inhibitor

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
PF-AKT400 (AKT protein kinase inhibitor) 是 ATP 竞争性的、选择性的 Akt 抑制剂,对 PKBα(IC50=0.5 nM) 的选择性比 PKA(IC50=450 nM) 高 900 倍。
T17169 Trk-IN-4

PF-6683324 isomer

Trk receptor Tyrosine Kinase/Adaptors
Trk-IN-4 is an effective pan-Trk inhibitor in cell-based assays (IC50s: 1.9 nM, 2.6 nM, and 1.1 nM for TrkA, TrkB, and TrkC, respectively).
TP1885L1 [(pF)Phe4]Nociceptin(1-13)NH2 acetate

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
[(pF)Phe4]Nociceptin(1-13)NH2 acetate 是一种选择性 NOP 受体激动剂,pKi 为 10.68,pEC50 为 9.31。 [(pF)Phe4]Nociceptin(1-13)NH2 acetate 对 δ、κ 和 μ 阿片受体具有高选择性(>3000 倍)。
TP2466 Platelet factor 4 (59-70)

PF4 (59-70)

Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis.
TP1885 [(pF)Phe4]Nociceptin(1-13)NH2

Highly potent and selective nociceptin/orphanin FQ receptor (OP4) agonist peptide (pKi = 10.68; pEC50 = 9.80). Displays > 8000-fold selectivity over δ, κ, and μ opioid receptors and has relatively long lasting pronociceptive, hypotensive, negative inotrop
T39299 (3S,4S)-PF-06459988

(3S, 4S)-PF-06459988 is the less active S enantiomer of PF-06459988, which is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 exhibits excellent selectivity against EGFR wild-type due to its minimally reactive electrophile, which reduces the likelihood of off-target labeling.
T63641 (3S,4R)-PF-6683324

(3S,4R)-PF-6683324 是原肌球蛋白相关激酶 (Trk) 抑制剂,对疼痛和癌症表现出研究潜力。
T2001 PF-573228

PF 573228

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-573228是一种选择性的 FAK 抑制剂,对 FAK 纯化重组催化片段的 IC50值为4 nM。
T76705 Utomilumab

PF 05082566,PF-2566

TNF Apoptosis
Utomilumab (PF 05082566) 是一种人源化靶向T 细胞共刺激受体4-1BB/CD137的 IgG2 抗体,也是一种 4-1BB/CD137 激动剂。Utomilumab 具有抗肿瘤活性,可用于研究晚期恶性肿瘤患者。
T69526 PF-07258669

Melanocortin Receptor GPCR/G Protein; Neuroscience
PF-07258669 是一种选择性黑皮质素 4 受体 (MC4) 拮抗剂,可用于研究恶病质和食欲衰退。
TQ0167 Zimlovisertib

PF-06650833,PF06650833

IRAK Immunology/Inflammation; NF-κB
Zimlovisertib (PF-06650833) 是口服有活性的、可生物利用的白介素-1 受体相关激酶 4 (IRAK4) 选择性抑制剂,其IC50=0.2 nM,在 PBMC 分析中,IC50=2.4 nM。它具有研究类淋巴瘤、风湿性关节炎、狼疮等疾病的潜力。
T16481 PF-04995274

5-HT Receptor GPCR/G Protein; Neuroscience
PF-04995274 是强效,高亲和力,口服活性血清素 4 受体的部分激动剂。它是可脑渗透的,可用于与阿尔茨海默症相关的认知障碍的研究。
T6514 Glasdegib

PF-04449913

Hedgehog/Smoothened; Smo GPCR/G Protein; Stem Cells
Glasdegib (PF-04449913) 是一种口服具有活力的 smoothened 抑制剂,能够结合到人 SMO(181-787氨基酸位点),IC50=4 nM。
T19649 PF-06273340

PF 6273340,PF 06273340,PF6273340,PF-6273340

Trk receptor Tyrosine Kinase/Adaptors
PF-06273340 是一种口服具有活力的、具有选择性的外周限制性Trk 泛抑制剂。
T9458 PF-00835231

SARS-CoV Microbiology/Virology
PF-00835231 是一种 CoV-2 半胱氨酸 3C 样蛋白酶抑制剂,对 SARS CoV-2 和 SARS CoV-1 3CLpro 的 IC50 分别为 0.27 nM 和 4 nM。它用于抗 SARS-CoV-2/COVID-19 的研究。
T4230 PF-3758309 hydrochloride

PF-03758309 hydrochloride

Apoptosis; PAK Apoptosis; Cytoskeletal Signaling
PF-3758309 hydrochloride (PF-03758309 hydrochloride) 是一种口服的、可逆的 ATP 竞争性PAK4抑制剂,Kd 为 2.7 nM,Ki 为 18.7 nM。它抑制锚定独立生长、诱导凋亡、细胞骨架重塑和抑制增殖,具有 PAK4 抑制剂的预期细胞功能。
T41275 PF-04753299

Others Others
PF-04753299 是一种有效的、选择性的LpxC 抑制剂。PF-04753299 对淋球菌分离株具有杀菌作用,对大肠杆菌、铜绿假单胞菌和肺炎菌株的抑制的MIC90值分别为 2 μg/ml、4 μg/ml 和 16 μg/ml。PF-04753299 用于革兰氏阴性菌感染的研究。
T28369 PF-06278121

PF6278121,PF 6278121,PF-6278121

PF-06278121 is a potent and selective Trk inhibitor. PF-06278121 shows Trk A/B IC50 = 4/94 nM (enzymatic assay), Trk A/B/C IC50 = 13/7/6 nM (PathHunter cell assay).
T12415 PF-00446687

Others Others
PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).
TP1667 Platelet Factor 4 (58-70), human

Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues.
T39248 PF-06426779

PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.
T60921 PF-07038124

PF-07038124是 PDE4 的抑制剂。PF-07038124 对 PDE4B2 的 IC50值为0.5 nM。PF-07038124 对IFNγ、IL-4 和 IL-13具有抑制活性,IC50值分别为 1.06、4.1 和125 nM。
T70896 PF05020182

PF05020182 is novel potent and selective Kv7.2/4 potassium channel opener. PF-05020182 (2) significantly inhibits convulsions in the MES assay at doses tested, consistent with in vitro activity measure. The physiochemical properties, in vitro and in vivo activities of PF-05020182 support further development as an adjunctive treatment of refractory epilepsy. Facilitating activation, or delaying inactivation, of the native Kv7 channel reduces neuronal excitability, which may be beneficial in cont...
T11606 ICA-105665

PF-04895162

Others Others
ICA-105665 (PF-04895162) 是一种有效的口服活性的神经元 Kv7.2/7.3和 Kv7.3/7.5钾通道激动剂。ICA-105665 在人肝细胞中具有低细胞毒性潜力,但抑制肝线粒体功能和胆盐输出蛋白 (BSEP) 转运 (IC50为 311 μM)。ICA-105665 可穿透中枢神经系统 (CNS)并具有抗癫痫作用。

化合物

PF-06291874
Cat.No: TQ0239
Synonym: Glucagon receptor antagonists-4
Target: Glucagon Receptor
CP-380736
Cat.No: T19814
Synonym: PF 00520893,CP380736,PF00520893,6,7-二甲氧乙氧基喹唑啉-4-酮,CP 380736,PF-00520893
Target: EGFR
PF-AKT400
Cat.No: T5508
Synonym: (S)-N-[[3-氨基-1-(5-乙基-7H-吡咯并[2,3-D]嘧啶-4-基)吡咯烷-3-基]甲基]-2,4-二氟苯甲酰胺,AKT protein kinase inhibitor
Target: Akt
Trk-IN-4
Cat.No: T17169
Synonym: PF-6683324 isomer
Target: Trk receptor
[(pF)Phe4]Nociceptin(1-13)NH2 acetate
Cat.No: TP1885L1
Synonym:
Target: Opioid Receptor
Platelet factor 4 (59-70)
Cat.No: TP2466
Synonym: PF4 (59-70)
Target:
[(pF)Phe4]Nociceptin(1-13)NH2
Cat.No: TP1885
Synonym:
Target:
(3S,4S)-PF-06459988
Cat.No: T39299
Synonym:
Target:
(3S,4R)-PF-6683324
Cat.No: T63641
Synonym:
Target:
PF-573228
Cat.No: T2001
Synonym: PF 573228
Target: Apoptosis, FAK
Utomilumab
Cat.No: T76705
Synonym: PF 05082566,PF-2566
Target: TNF
PF-07258669
Cat.No: T69526
Synonym:
Target: Melanocortin Receptor
Zimlovisertib
Cat.No: TQ0167
Synonym: PF-06650833,PF06650833
Target: IRAK
PF-04995274
Cat.No: T16481
Synonym:
Target: 5-HT Receptor
Glasdegib
Cat.No: T6514
Synonym: PF-04449913
Target: Hedgehog/Smoothened, Smo
PF-06273340
Cat.No: T19649
Synonym: PF 6273340,PF 06273340,PF6273340,PF-6273340
Target: Trk receptor
PF-00835231
Cat.No: T9458
Synonym:
Target: SARS-CoV
PF-3758309 hydrochloride
Cat.No: T4230
Synonym: PF-03758309 hydrochloride
Target: Apoptosis, PAK
PF-04753299
Cat.No: T41275
Synonym:
Target: Others
PF-06278121
Cat.No: T28369
Synonym: PF6278121,PF 6278121,PF-6278121
Target:
PF-00446687
Cat.No: T12415
Synonym:
Target: Others
Platelet Factor 4 (58-70), human
Cat.No: TP1667
Synonym:
Target:
PF-06426779
Cat.No: T39248
Synonym:
Target:
PF-07038124
Cat.No: T60921
Synonym:
Target:
PF05020182
Cat.No: T70896
Synonym:
Target:
ICA-105665
Cat.No: T11606
Synonym: PF-04895162
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00741 CXCL4 Protein, Human, Recombinant

PF-4,platelet factor 4,SCYB4<...

Human E. coli
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a...
TMPK-00012 CXCL4 Protein, Human, Recombinant (His & Avi)

PF-4,CXCL4,SCYB4,Oncosta...

Human E. coli
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Human, Recombinant (His & Avi) is expresse...
TMPK-01248 CXCL4 Protein, Mouse, Recombinant (hFc)

PF-4,CXCL4,SCYB4,Oncosta...

Mouse HEK293 Cells
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Mouse, Recombinant (hFc) is expressed in H...
TMPK-00014 CXCL4 Protein, Human, Recombinant (hFc)

Iroplact,CXCL4,Oncostatin-A,PF-4,...

Human HEK293 Cells
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Human, Recombinant (hFc) is expressed in H...
TMPK-00013 CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated

SCYB4,MGC138298,PF-4,Iroplact,Onc...

Human E. coli
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylat...
TMPJ-00012 CXCL4 Protein, Human, Recombinant (His)

SCYB4,PF4,Iroplact,Platelet Facto...

Human HEK293 Cells
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokin...
TMPH-03121 CXCL4 Protein, Pig, Recombinant (His & Myc)

SCYB4,CXCL4,PF4,Platelet...

Sus scrofa (Pig) E. coli
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation. CXCL4 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is P30034.
TMPY-04622 PF4V1 Protein, Human, Recombinant (mFc)

PF4A,CXCL4V1,platelet factor ...

Human HEK293 Cells
PF4V1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.6 kDa and the accession number is P10720.
TMPY-00749 FGF-2 Protein, Human, Recombinant

fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF

Human E. coli
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPJ-00864 VEGF165 Protein, Human, Recombinant

Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子,VEGF...

Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi)

血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,V

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

vascular endothelial growth factor A,血管内皮生长因子

Human,Cynomolgus HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-02893 NT5C3A/NT5C3 Protein, Human, Recombinant

P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...

Human E. coli
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPK-00424 CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

LCA,LY5,EC 3.1.3.48,CD45,L-CA,T200,CD4...

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPK-00822 VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,V...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPJ-00782 Amyloid Precursor Protein, Human, Recombinant (hFc)

Amyloid Precursor,Amyloid Precursor Protein 695,APP695

Human HEK293 Cells
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPY-04754 CASK Protein, Human, Recombinant

CMG,LIN2,MRXSNA,CAMGUK,calcium/calmodulin-dependent serine p...

Human Baculovirus Insect Cells
CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-00225 CLEC9A Protein, Mouse, Recombinant (hFc)

C-type lectin domain family 9, member A,9830005G06Rik,DNGR-1

Mouse HEK293 Cells
CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4.
TMPY-01117 MRAP Protein, Human, Recombinant (hFc)

FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...

Human HEK293 Cells
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPJ-00233 CD200R1/CRTR2 Protein, Human, Recombinant (His)

Cell Surface Glycoprotein CD200 Receptor 1,OX2R,MOX2R,CD200 ...

Human HEK293 Cells
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytopla...
TMPK-00423 CD45 Protein, Human, Recombinant (His & Avi)

CD45R,LY5,EC 3.1.3.48,B220,CD45,T...

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPJ-01333 TEM8/ANTXR1 Protein, Human, Recombinant (His)

ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax Toxin Rec...

Human HEK293 Cells
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPY-05598 Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated

SIGLEC2,SIGLEC-2,CD22 molecule

Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4.
TMPY-04471 APEG1 Protein, Human, Recombinant (His)

SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG...

Human E. coli
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre...
TMPK-00702 ANTXR2 Protein, Human, Recombinant (His)

cI-35,Antxr2,JHS,CMG-2,CMG2,JHF,HFS,ISH

Human HEK293 Cells
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultured in vitro. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.
TMPY-01033 IL-32 Protein, Human, Recombinant (isoform alpha, His)

IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform...

Human HEK293 Cells
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-01823 PTK9 Protein, Human, Recombinant

MGC41876,twinfilin actin binding protein 1,A6,MGC23...

Human E. coli
PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4.
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc)

VEGFR1,VEGFR-1,fms-related tyrosine kinase 1,FLT-1,FLT

Human HEK293 Cells
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
TMPY-04563 CASK Protein, Human, Recombinant (His & GST)

calcium/calmodulin-dependent serine protein kinase (MAGUK fa...

Human Baculovirus Insect Cells
CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4.
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His)

CASP10,FAS-Associated Death Domain Protein Interleukin-1B-Co...

Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca...
TMPY-01822 PTK9 Protein, Human, Recombinant (His & GST)

PTK9,MGC41876,A6,MGC23788,twinfilin actin binding p...

Human E. coli
PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
TMPY-04565 SRPK3 Protein, Human, Recombinant (His & GST)

MSSK1,MGC102944,STK23,MSSK-1,SRSF protein ...

Human Baculovirus Insect Cells
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-...
TMPJ-01188 CORO6 Protein, Human, Recombinant (His)

Coronin-6,Clipin-E,CORO6

Human E. coli
Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are a family of conserved actin-binding proteins originally identified in the actin-rich structure of the amoeba Dictyostelium discoideum . To date, seven members of coronins have been identified in mammals, and most exhibit tissue-specific distribution patterns. Coronin 6 is promin...
TMPJ-00410 CD45R0 Protein, Human, Recombinant (His)

CD45 antigen,L-CA,protein tyrosine phosphatase, rec...

Human HEK293 Cells
CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPY-00711 CD45 Protein, Human, Recombinant (hFc)

GP180,L-CA,LY5,T200,protein tyrosine phosphatase, receptor t...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4.
TMPY-00380 ANTXR2 Protein, Human, Recombinant (hFc)

HFS,JHF,anthrax toxin receptor 2,ISH,CMG-2,CMG2

Human HEK293 Cells
ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4.
TMPY-01933 CHI3L2 Protein, Human, Recombinant (His)

YKL-39,CHIL2,chitinase 3 like 2,YKL39

Human HEK293 Cells
Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, followed by synoviocytes, lung and heart. YKL-39/CHI3L2 is not detected in spleen, pancreas, and liver. YKL-39/CHI3L2 may also be expressed in developing brain and placenta. YKL-39/CHI3L2, a cartilage-related protein, is found to induce arthritis accompanied by pathologic changes in b...
TMPK-01362 SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated

MYD1,SIRP α V4,PTPNS1,BIT,SHPS1,SIRP alpha,SHPS-1,S...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01356 SIRP alpha V4 Protein, Human, Recombinant (His & Avi)

BIT,SIRP α V4,MFR,SHPS1,SIRPA,SIRP α,P84,M...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

CXCL4 Protein, Human, Recombinant
Cat.No: TMPY-00741
Species: Human
Expression System: E. coli
CXCL4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00012
Species: Human
Expression System: E. coli
CXCL4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01248
Species: Mouse
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00014
Species: Human
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00013
Species: Human
Expression System: E. coli
CXCL4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00012
Species: Human
Expression System: HEK293 Cells
CXCL4 Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03121
Species: Sus scrofa (Pig)
Expression System: E. coli
PF4V1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04622
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Human, Recombinant
Cat.No: TMPY-00749
Species: Human
Expression System: E. coli
VEGF165 Protein, Human, Recombinant
Cat.No: TMPJ-00864
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00823
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293 Cells
NT5C3A/NT5C3 Protein, Human, Recombinant
Cat.No: TMPY-02893
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00424
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00822
Species: Human
Expression System: HEK293 Cells
Amyloid Precursor Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00782
Species: Human
Expression System: HEK293 Cells
CASK Protein, Human, Recombinant
Cat.No: TMPY-04754
Species: Human
Expression System: Baculovirus Insect Cells
CLEC9A Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00225
Species: Mouse
Expression System: HEK293 Cells
MRAP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01117
Species: Human
Expression System: HEK293 Cells
CD200R1/CRTR2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00233
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00423
Species: Human
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01333
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05598
Species: Human
Expression System: HEK293 Cells
APEG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04471
Species: Human
Expression System: E. coli
ANTXR2 Protein, Human, Recombinant (His)
Cat.No: TMPK-00702
Species: Human
Expression System: HEK293 Cells
IL-32 Protein, Human, Recombinant (isoform alpha, His)
Cat.No: TMPY-01033
Species: Human
Expression System: HEK293 Cells
PTK9 Protein, Human, Recombinant
Cat.No: TMPY-01823
Species: Human
Expression System: E. coli
FLT1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00119
Species: Human
Expression System: HEK293 Cells
CASK Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04563
Species: Human
Expression System: Baculovirus Insect Cells
Caspase-10 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01256
Species: Human
Expression System: E. coli
PTK9 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-01822
Species: Human
Expression System: E. coli
SRPK3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04565
Species: Human
Expression System: Baculovirus Insect Cells
CORO6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01188
Species: Human
Expression System: E. coli
CD45R0 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00410
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00711
Species: Human
Expression System: HEK293 Cells
ANTXR2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00380
Species: Human
Expression System: HEK293 Cells
CHI3L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01933
Species: Human
Expression System: HEK293 Cells
SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01362
Species: Human
Expression System: HEK293 Cells
SIRP alpha V4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01356
Species: Human
Expression System: HEK293 Cells
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